Mark started academic life as a medical microbiologist, with training in medicine (BA from Cambridge MBBS, MD from London) and laboratory research (PhD in Gordon Dougan’s lab at Imperial College, during which he captained the winning team in University Challenge).
Tom is a Professor at Cardiff University. He is a Big Data Biologist who has a background in the population genomics and molecular epidemiology of pathogenic bacteria. He obtained his PhD at Imperial, and was Postdoctoral Fellow at the Wellcome Trust Sanger Institute from 2010 to 2012.
Nick is Professor of Microbial Genomics and Bioinformatics at the University of Birmingham. His research explores the use of cutting-edge genomics and metagenomics approaches to the diagnosis, treatment and surveillance of infectious disease. Nick has so far used high-throughput sequencing to investigate outbreaks of important Gram-negative multi-drug resistant pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii and Shiga-toxin producing Escherichia coli. His current work focuses on the genetic diversity of Pseudomonas aeruginosa infection in chronic lung diseases such as cystic fibrosis as a diagnostic and prognostic marker. A more general aim is to develop bioinformatics tools to aid the interpretation of genome and metagenome-scale data in routine clinical practice.
Andrew is the Head of Informatics at the Quadram Institute where his group provides support for Informatics and Bioinformatics. He has an interest in high performance computing and high throughput bioinformatics sequence analysis pipelines. Andrew has a BSc in Software Engineering and a PhD in Computer Science on the topic of Distributed Computing Systems. He was a Post-Doctoral research fellow at the National College of Ireland working on machine learning. After moving to the Wellcome Trust Sanger Institute, he worked on Laboratory Information Systems. In 2011 he became the Principal Computer Programmer in the Pathogen Informatics group supporting the Infection Genomics group at Sanger. His work focused on building and managing bioinformatics sequence analysis pipelines for pathogenic organisms using both short and long read sequencing technologies. In 2018 he moved to the Quadram Institute.
Chris comes from a physical-sciences background, with a PhD in theoretical physics. In recent years he has successfully turned his attention to bioinformatics problems in sequence-based analyses of microbial communities, with two highly cited papers on removing noise from pyrosequenced amplicons. He held a five-year EPSRC Career Acceleration Fellowship (2009-2014) entitled ‘Pioneering the new genomics era in environmental microbiology for engineering design.’ Chris is interested in Bayesian statistical approaches in microbial bioinformatics.
In June 2016 Andy was promoted to Assistant Professor at Warwick Medical School. He then moved to the University of Leicester in September 2017 to a setup a lectureship.
Sam is Professor and director of Bioinformatics (Milner Centre for Evolution) at the University of Bath and Co-I of CLIMB-BIG-DATA–the UKs largest cloud-based system for the analysis of microbial genomes.
Martin Antonio is Unit Molecular Biologist and Principal Investigator at the Medical Research Council Unit the Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia. He serves as the Director, the WHO collaborating Centre for New Vaccines Surveillance and Heads the WHO Regional Reference Laboratory for Invasive Bacterial Diseases (IBD) for West and Central Africa. Martin also holds the position of Honorary Professor at Warwick Medical School, University of Warwick, UK. He is a Fellow of the Royal College of Pathologists (London, UK) and Honorary Fellow of the Royal College of Physicians (London, UK). His research is focused on the leverage of new molecular technologies in diagnosis of tropical infections, investigation of microbial transmission and clinical trials. Martin's group has led and participated in a growing number of large-scale international research projects, serving as the WHO reference laboratory for pneumococcal disease and establishing large disease surveillance platforms for bacterial infections across Africa.
Simon is Head of IT and Data Science at the Swansea University. He is a systems architect with experience in the NHS and academia. He is responsible for delivering the technical workstream for Swansea as part of the UK network of health e-research centres of excellence.
Anna has a background in the physical sciences, earning an MPhys in theoretical physics and a PhD in NEGF simulations of nanotransistors. Since 2017, she has been working as a Research Software Engineer in biosciences and medicine. She has an interest in developing open-source software for bioinformatics and big data problems in microbiology. In her role as a Research Software Engineer for CLIMB-BIG-DATA, she aims to create a repository of software and tools for microbial bioinformatics to support the CLIMB-BIG-DATA community.
Andrew Smith is Research Software Engineer for CLIMB-BIG-DATA, working at the University of Birmingham. He is currently working on the user interface (Bryn), on the ticketing system and on the S3 object storage.
The CLIMB-BIG-DATA project includes funding for two Research Softwares Engineers, who will provide vital skills for microbial genomics research including mathematical modelling, population genetics, computer science and bioinformatics.
Lisa has a BSc and an MSc in Molecular Biology, and a PhD in Epigenomics. In 2014 she became a project manager for the Italian €30million, 70-partner EPIGEN-CNR Flagship Project, which ended in summer 2019. She moved to the Quadram in 2017 to manage the MRC-CLIMB project. She has a solid experience in the coordination, follow-up and reporting of the administrative, financial and scientific aspects of a Project, as well as in the organization and follow-up of scientific and dissemination events.
Mavis joined the CLIMB-BIG-DATA team in October 2021 as a Project Manager (part-time) with focus on the finance and project administration. Before joining the team, she worked as a project manager at the MRC Unit the Gambia at London School of Hygiene and Tropical Medicine for over six years, where she garnered extensive proficiency in the management and administration of a diverse portfolio of research projects from the grant application stage to successful research completion.
Michaela is a bioinformatician working at the QIB, she joined the CLIMB-BIG-DATA team in April 2021.
University of Birmingham
University of Warwick
Nabil is a Bioinformatics Scientific Programmer within the Core Bioinformatics / Page group at the Quadram Institute. He has dedicated his professional life to improving bioinformatic analyses and then using these improvements to find new insight into microbial pathogens. His current duties include developing bioinformatics infrastructure and novel algorithms.
University of Birmingham
Simon works in research computing at the University of Birmingham. He has interests in high-performance computing, research data management. He set up up the Birmingham node of the CLIMB system and blogs about his experiences and frustrations with OpenStack on his personal blog, RoamingZebra.
CLIMB-BIG-DATA serves more than 1,000 users and over 300 research groups across at least 85 research institutions: