Mark Pallen

Principal Invesitgator

Mark Pallen started academic life as a medical microbiologist, with training in medicine (BA from Cambridge MBBS, MD from London) and laboratory research (PhD in Gordon Dougan’s lab at Imperial College, during which he captained the winning team in University Challenge).

Sam Sheppard

Principal Investigator

I am Professor and director of Bioinformatics (Milner Centre for Evolution) at the University of Bath and Co-PI of MRC CLIMB (Cloud Infrastructure for Microbial Bioinformatics)–the UKs largest cloud-based system for the analysis of microbial genomes.

Tom Connor


Tom is a Senior Lecturer at Cardiff University. He is a Big Data Biologist who has a background in the population genomics and molecular epidemiology of pathogenic bacteria. He obtained his PhD at Imperial, and was Postdoctoral Fellow at the Wellcome Trust Sanger Institute from 2010 to 2012.

Andy Millard


In June 2016 I was promoted to Assistant Professor at Warwick Medical School. I then moved to the University of Leicester in September 2017 to a setup a lectureship.

Steve Busby


Professor Busby has performed ground-breaking research on the molecular mechanisms that control gene expression in bacteria, particularly the regulation of transcription initiation in Escherichia coli.

Timothy Walsh


Walsh is Professor of Medical Microbiology and Antimicrobial Resistance at Cardiff University. His research focuses on the mechanisms, mobilization and spread of antimicrobial resistance, and his recent focus is on blending clinical and molecular epidemiology in low-middle income countries.

Daniel Falush

Research Fellow

Falush has performed pioneering work on statistical approaches to understand genetic variation within populations, aimed at elucidating evolutionary and historical processes. He has worked extensively with Sheppard and Achtman, with a research portfolio that spans diverse organisms, including many different kinds of bacteria. Falush has a superb track record in statistical and evolutionary genetics with many highly cited publications, including first/last-author papers in Science and PNAS, and a paper on inferring populations with nearly 3000 citations.

Nick Loman

Research Fellow

Nick is Professor of Microbial Genomics and Bioinformatics at the University of Birmingham. He works as an Independent Research Fellow in the Institute for Microbiology and Infection, sponsored by an MRC Special Training Fellowship in Biomedical Informatics. His research explores the use of cutting-edge genomics and metagenomics approaches to the diagnosis, treatment and surveillance of infectious disease. Nick has so far used high-throughput sequencing to investigate outbreaks of important Gram-negative multi-drug resistant pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii and Shiga-toxin producing Escherichia coli. His current work focuses on the genetic diversity of Pseudomonas aeruginosa infection in chronic lung diseases such as cystic fibrosis as a diagnostic and prognostic marker. A more general aim is to develop bioinformatics tools to aid the interpretation of genome and metagenome-scale data in routine clinical practice.

Christopher Quince

Research Fellow

Quince comes from a physical-sciences background, with a PhD in theoretical physics. In recent years he has successfully turned his attention to bioinformatics problems in sequence-based analyses of microbial communities, with two highly cited papers on removing noise from pyrosequenced amplicons. He held a five-year EPSRC Career Acceleration Fellowship (2009-2014) entitled ‘Pioneering the new genomics era in environmental microbiology for engineering design.’ Quince and Falush have common interests in Bayesian statistical approaches in microbial bioinformatics, which will prime collaborations.

The CLIMB project includes funding for three prestigious fellowships, covering salary and research costs. These fellowships are awarded for seven years at a time. Our fellows have vital skills for microbial genomics research including mathematical modelling, population genetics, computer science and bioinformatics.

Imran Hussain

Cloud Computing Manager

Swansea University

Radoslaw Poplawski

Cloud Computing Manager

University of Birmingham

Matt Bull

Cloud Computing Manager

Cardiff University

Sion Bayliss

Bioinformatics Systems Developer

University of Bath

Lisa Marchioretto

CLIMB Project Manager

Quadram Institute Bioscience

Ben Pascoe

Bath Centre Manager

University of Bath

Simon Ellwood-Thompson

Head of IT-Data Science

University of Swansea

Simon Thompson

Research Computing Infrastructure Architect

University of Birmingham

Simon Thompson works in research computing at the University of Birmingham. He has interests in high-performance computing, research data management. He set up up the Birmingham node of the CLIMB system and blogs about his experiences and frustrations with OpenStack on his personal blog, RoamingZebra.

Matt Ismail

We have over 300 research groups registered to use CLIMB including groups from the following institutes:

Aberystwyth University

Animal and Plant Health Agency

University of Bath

University of Bedfordshire

Queen's university Belfast

University of Birmingham

University of Cambridge

Cardiff University

University of East Anglia


University of Edinburgh

University of Exeter

University of Glasgow

University of Leeds

University of Leicester

University of Liverpool

Imperial College London

University College London

University of Manchester

Newcastle University

University of Northampton

University of Nottingham

Nottingham Trent University

Public Health England

University of Sheffield

University of Strathclyde

Swansea University

University of York

University of Warwick

University of Westminster

Wellcome Genome Campus

Wellcome Trust Sanger Institute