Mark Pallen started academic life as a medical microbiologist, with training in medicine (BA from Cambridge MBBS, MD from London) and laboratory research (PhD in Gordon Dougan’s lab at Imperial College, during which he captained the winning team in University Challenge).
Professor Sheppard holds a chair in Medical Microbiology & Infectious Diseases at Swansea University. Before joining Swansea in 2011 he worked for nearly 10 years in the laboratory of Professor Martin Maiden at the University of Oxford as a senior Research Associate and Wellcome Trust Career Development Fellow.
Professor Busby has performed ground-breaking research on the molecular mechanisms that control gene expression in bacteria, particularly the regulation of transcription initiation in Escherichia coli.
Tom is a Senior Lecturer at Cardiff University. He is a Big Data Biologist who has a background in the population genomics and molecular epidemiology of pathogenic bacteria. He obtained his PhD at Imperial, and was Postdoctoral Fellow at the Wellcome Trust Sanger Institute from 2010 to 2012.
Andrew is an Assistant Professor at Warwick Medical School. He has a background in environmental microbiology having completed a PhD at Warwick on "Cyanophages capable of infecting marine Synechococcus spp", this included the sequencing of the first marine cyanomyovirus in 2003.
Walsh is Professor of Medical Microbiology and Antimicrobial Resistance at Cardiff University. His research focuses on the mechanisms, mobilization and spread of antimicrobial resistance, and his recent focus is on blending clinical and molecular epidemiology in low-middle income countries.
Falush has performed pioneering work on statistical approaches to understand genetic variation within populations, aimed at elucidating evolutionary and historical processes. He has worked extensively with Sheppard and Achtman, with a research portfolio that spans diverse organisms, including many different kinds of bacteria. Falush has a superb track record in statistical and evolutionary genetics with many highly cited publications, including first/last-author papers in Science and PNAS, and a paper on inferring populations with nearly 3000 citations.
Nick works as an Independent Research Fellow in the Institute for Microbiology and Infection at the University of Birmingham, sponsored by an MRC Special Training Fellowship in Biomedical Informatics. His research explores the use of cutting-edge genomics and metagenomics approaches to the diagnosis, treatment and surveillance of infectious disease. Nick has so far used high-throughput sequencing to investigate outbreaks of important Gram-negative multi-drug resistant pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii and Shiga-toxin producing Escherichia coli. His current work focuses on the genetic diversity of Pseudomonas aeruginosa infection in chronic lung diseases such as cystic fibrosis as a diagnostic and prognostic marker. A more general aim is to develop bioinformatics tools to aid the interpretation of genome and metagenome-scale data in routine clinical practice.
Quince comes from a physical-sciences background, with a PhD in theoretical physics. In recent years he has successfully turned his attention to bioinformatics problems in sequence-based analyses of microbial communities, with two highly cited papers on removing noise from pyrosequenced amplicons. He held a five-year EPSRC Career Acceleration Fellowship (2009-2014) entitled ‘Pioneering the new genomics era in environmental microbiology for engineering design.’ Quince and Falush have common interests in Bayesian statistical approaches in microbial bioinformatics, which will prime collaborations.
The CLIMB project includes funding for three prestigious fellowships, covering salary and research costs. These fellowships are awarded for seven years at a time. Our fellows have vital skills for microbial genomics research including mathematical modelling, population genetics, computer science and bioinformatics.
Simon Thompson works in research computing at the University of Birmingham. He has interests in high-performance computing, research data management. He is currently setting up the Birmingham node of the CLIMB system and is blogging about his experiences and frustrations with OpenStack on his personal blog, RoamingZebra.
We have over 100 research groups registered to use CLIMB including groups from the following institutes:
Animal and Plant Health Agency
University of Bath
University of Bedfordshire
Queen's university Belfast
University of Birmingham
University of Cambridge
University of East Anglia
University of Edinburgh
University of Exeter
University of Glasgow
University of Leeds
University of Leicester
University of Liverpool
Imperial College London
University College London
University of Manchester
University of Northampton
University of Nottingham
Nottingham Trent University
Public Health England
University of Sheffield
University of Strathclyde
University of York
University of Warwick
University of Westminster
Wellcome Genome Campus
Wellcome Trust Sanger Institute